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Costa and Stevenson (1984) with the administration of equine chorionic gonadotropin (eCG) and pregnant mares serum gonadotropin (PMSG) showed that these components increases ovarian concentration of free LC and ALC, which shows the interaction between the direct and indirect mechanisms through cellular and hormonal regulations [82]

Under arsenite stress, this METTL3/YTHDF2 interaction is inhibited, which stabilizes CHAC1 mRNA and increases its expression (Qiu et al., 2025)

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Unlike the injectable pen, the pill can be stored at room temperature and does not require refrigeration, making it easier to carry during flights or work trips

This profound genomic modulation underscores its growing significance in anti-aging, epigenetic, and longevity research models